MIMESIS Newsletter #4: A novel systems biology approach to develop preclinical assets
MIMESIS NEWSLETTER #4, December 2018
After two years, ENYO Pharma’s EU funded MIMESIS project was a real success and has delivered several promising new drug development starting points most significantly for RSV and ICD.
MIMESIS is a research and innovation project coordinated by ENYO Pharma and funded under the highly selective H2020 – SMEInstrument – Phase 2 call that aims at: “Dedicated support to biotechnology SMEs closing the gap from lab to market”.
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- The first patient dosed in the Phase 2 ALPESTRIA-1 clinical study of Vonafexor for Alport syndrome
- The Phase 2 ALPESTRIA-1 clinical study has started with Vonafexor on Alport syndrome
- Orphan Drug Designation (ODD) granted to Vonafexor for Alport syndrome by both the European Medicines Agency (EMA) and the U.S. Food and Drug Administration (FDA)
- New publication: Hepatic and renal improvements with FXR agonist Vonafexor in individuals with suspected fibrotic NASH
- New publication : An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters